Embosphere Microspheres

CLINICALLY PROVEN ROUND EMBOLIC

“Given the known risk of recurrence in patients with persistent tumor enhancement after UAE, it is concluded that tris-acryl gelatin microspheres should be the preferred agent for UAE at this time.”

Siskin GP, et al. Leiomyoma Infarction after Uterine Artery Embolization:
A Prospective Randomized Study Comparing Tris-acryl Gelatin Microspheres versus Polyvinyl Alcohol Microspheres. J Vasc Interv Radiol 2008; 19: 58-65.

“The primary embolic agent used was calibrated microspheres in 73% of cases (either Embosphere or Embosphere Gold, Biosphere Medical, Rockland, MA)…”

Siskin GP, et al. Leiomyoma Infarction after Uterine Artery Embolization:
Worthington-Kirsch R, et al. The Fibroid Registry for Outcomes Data (FIBROID) for Uterine Embolization – Short Term Outcomes. Obstet & Gynecol 2005; 106: 52-9.

[Patients] treated with TAGM were significantly more likely to have complete infarction of all leiomyomas…The use of spherical PVA particles in the manner described herein results in an unacceptably high rate of failed tumor infarction in UAE.

Spies JB, et al. Spherical Polyvinyl Alcohol Versus Trisacryl Gelatin Microspheres for Uterine Artery Embolization for Leiomyomas:
Results of a Limited Randomized Comparative Study. J Vasc Interv Radiol 2005;16:1431-7.

Over the long term, UFE using TAGM is effective and safe, with high levels of durable symptom control, improved health-related quality of life and patient satisfaction.

Spies JB, et al. Long-Term Outcome from Uterine Fibroid Embolization
Using Tris-Acryl Gelatin Microspheres. J Vasc Interv Radiol 2007; 18: 203-7

REGULATORY INFORMATION

USA

Embosphere Microspheres are indicated for use in the embolization of:

• Hypervascular tumors, including symptomatic uterine fibroids
• Prostatic arteries for symptomatic Benign Prostatic Hyperplasia (BPH)
• Arteriovenous malformations
• Blood vessels to occlude blood flow to control bleeding/hemorrhaging in the peripheral vasculature

European Union

Embosphere Microspheres are designed to occlude blood vessels, for therapeutic or preoperative purposes, in the following  procedures:

• Embolisation of hypervascular tumours and processes, including uterine fibroids, meningiomas,etc.
• Embolisation of the prostate arteries for relief of symptoms related to Benign Prostatic Hyperplasia.
• Embolisation of arteriovenous malformations.
• Haemostatic embolisation.

• Most clinically studied round embolic
• Backed by more than 200 clinical articles¹—far more than all other round embolics combined
• Consistent and durable clinical results with over 10 years of clinical experience
• Technology used in over 340,000 procedures worldwide¹

¹ Data as of January 2016